Due to gene mutations, slight variations can occur even within the significant blood types. Researchers in genomics published a 2022 study that revealed a strong link between early stroke and the gene of the subgroup A1. The researchers gathered data from 48 studies that included approximately 17,000 stroke victims and almost 600,000 controls. We had participants aged between 18 and 59. Two locations were strongly linked to an increased risk of stroke. The other was located at the same spot as where blood type genes are. The second analysis revealed that those with a blood type A gene variation had a 16 percent higher chance of suffering a stroke by the time they reached 60 years old than people of different blood types. The cancer risk was reduced by 12 percent for those with the gene group O1. Researchers noted that although the risk for stroke is slightly higher in those with type A, there’s no reason to be extra vigilant or screen this group. Steven Kittner vascular neurologist and senior author at the University of Maryland said: “We don’t yet know why blood type A conferred a greater risk.”The cause of this condition likely has to do with blood clotting factors such as platelets, cells that line blood vessels, and other proteins circulating in the body. “The role of plasma in blood clot formation.”Let’s look at the results of this study in context. In the US, each year, fewer than 800,000 people suffer a stroke. Around three of four incidents occur among people aged 65 and over, while the risk doubles every 10 years after 55. The study also included people from North America, Europe, Japan, and Australia. People of non-European descent only made up 35% of the participants. A more diverse sampling in future studies could help clarify the meaning of the findings. Kittner stated, “We need to do more studies to understand the mechanism of stroke risk.”A vital result of this study was the comparison of people with a history of strokes before 60 years of age and those who experienced a stroke later in life. The researchers looked at a database of approximately 9,300 stroke victims over 60 years old and 25,000 control subjects over 60. I didn’t suffer a stroke. The increased stroke risk in type A was not significant in strokes occurring late in life. This suggests that strokes occurring early may be more serious. The mechanisms used to cause the events later in life may differ. According to the authors, strokes are more often caused by other factors than a buildup of fat deposits (a condition called atherosclerosis). Factors affecting clot formation can cause a thrombosis.
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